Pesquisa | Biblioteca Virtual em Saúde

1.

Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.

Han, Hong; Best, Andrew J; Braunschweig, Ulrich; Mikolajewicz, Nicholas; Li, Jack Daiyang; Roth, Jonathan; Chowdhury, Fuad; Mantica, Federica; Nabeel-Shah, Syed; Parada, Guillermo; Brown, Kevin R; O'Hanlon, Dave; Wei, Jiarun; Yao, Yuxi; Zid, Abdelrahman Abou; Comsa, Lim Caden; Jen, Mark; Wang, Jenny; Datti, Alessandro; Gonatopoulos-Pournatzis, Thomas; Weatheritt, Robert J; Greenblatt, Jack F; Wrana, Jeffrey L; Irimia, Manuel; Gingras, Anne-Claude; Moffat, Jason; Blencowe, Benjamin J.

Mol Cell ; 82(16): 2982-2999.e14, 2022 08 18.

Artigo em Inglês | MEDLINE | ID: mdl-35914530

2.

A highly conserved program of neuronal microexons is misregulated in autistic brains.

Irimia, Manuel; Weatheritt, Robert J; Ellis, Jonathan D; Parikshak, Neelroop N; Gonatopoulos-Pournatzis, Thomas; Babor, Mariana; Quesnel-Vallières, Mathieu; Tapial, Javier; Raj, Bushra; O'Hanlon, Dave; Barrios-Rodiles, Miriam; Sternberg, Michael J E; Cordes, Sabine P; Roth, Frederick P; Wrana, Jeffrey L; Geschwind, Daniel H; Blencowe, Benjamin J.

Cell ; 159(7): 1511-23, 2014 Dec 18.

Artigo em Inglês | MEDLINE | ID: mdl-25525873

3.

Sugar defeats the Hippo: Glycogen regulation of the Hippo pathway in liver.

Nguyen-Lefebvre, Anh Thu; Bhat, Mamatha; Wrana, Jeffrey L.

Mol Cell ; 81(23): 4768-4770, 2021 12 02.

Artigo em Inglês | MEDLINE | ID: mdl-34861187

4.

Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration.

Luga, Valbona; Zhang, Liang; Viloria-Petit, Alicia M; Ogunjimi, Abiodun A; Inanlou, Mohammad R; Chiu, Elaine; Buchanan, Marguerite; Hosein, Abdel Nasser; Basik, Mark; Wrana, Jeffrey L.

Cell ; 151(7): 1542-56, 2012 Dec 21.

Artigo em Inglês | MEDLINE | ID: mdl-23260141

5.

An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.

Gabut, Mathieu; Samavarchi-Tehrani, Payman; Wang, Xinchen; Slobodeniuc, Valentina; O'Hanlon, Dave; Sung, Hoon-Ki; Alvarez, Manuel; Talukder, Shaheynoor; Pan, Qun; Mazzoni, Esteban O; Nedelec, Stephane; Wichterle, Hynek; Woltjen, Knut; Hughes, Timothy R; Zandstra, Peter W; Nagy, Andras; Wrana, Jeffrey L; Blencowe, Benjamin J.

Cell ; 147(1): 132-46, 2011 Sep 30.

Artigo em Inglês | MEDLINE | ID: mdl-21924763

6.

Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell.

Ayyaz, Arshad; Kumar, Sandeep; Sangiorgi, Bruno; Ghoshal, Bibaswan; Gosio, Jessica; Ouladan, Shaida; Fink, Mardi; Barutcu, Seda; Trcka, Daniel; Shen, Jess; Chan, Kin; Wrana, Jeffrey L; Gregorieff, Alex.

Nature ; 569(7754): 121-125, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-31019301

7.

Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors.

Han, Hong; Braunschweig, Ulrich; Gonatopoulos-Pournatzis, Thomas; Weatheritt, Robert J; Hirsch, Calley L; Ha, Kevin C H; Radovani, Ernest; Nabeel-Shah, Syed; Sterne-Weiler, Tim; Wang, Juli; O'Hanlon, Dave; Pan, Qun; Ray, Debashish; Zheng, Hong; Vizeacoumar, Frederick; Datti, Alessandro; Magomedova, Lilia; Cummins, Carolyn L; Hughes, Timothy R; Greenblatt, Jack F; Wrana, Jeffrey L; Moffat, Jason; Blencowe, Benjamin J.

Mol Cell ; 65(3): 539-553.e7, 2017 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-28157508

8.

YAP establishes epiblast responsiveness to inductive signals for germ cell fate.

Kagiwada, Saya; Aramaki, Shinya; Wu, Guangming; Shin, Borami; Kutejova, Eva; Obridge, David; Adachi, Kenjiro; Wrana, Jeffrey L; Hübner, Karin; Schöler, Hans R.

Development ; 148(20)2021 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-34528691

9.

The secret life of Smad4.

Wrana, Jeffrey L.

Cell ; 136(1): 13-4, 2009 Jan 09.

Artigo em Inglês | MEDLINE | ID: mdl-19135880

10.

Regulation of planar cell polarity by Smurf ubiquitin ligases.

Narimatsu, Masahiro; Bose, Rohit; Pye, Melanie; Zhang, Liang; Miller, Bryan; Ching, Peter; Sakuma, Rui; Luga, Valbona; Roncari, Luba; Attisano, Liliana; Wrana, Jeffrey L.

Cell ; 137(2): 295-307, 2009 Apr 17.

Artigo em Inglês | MEDLINE | ID: mdl-19379695

11.

Regulation of homeostasis and regeneration in the adult intestinal epithelium by the TGF-ß superfamily.

Fink, Mardi; Wrana, Jeffrey L.

Dev Dyn ; 252(4): 445-462, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-35611490

12.

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming.

Hirsch, Calley L; Coban Akdemir, Zeynep; Wang, Li; Jayakumaran, Gowtham; Trcka, Dan; Weiss, Alexander; Hernandez, J Javier; Pan, Qun; Han, Hong; Xu, Xueping; Xia, Zheng; Salinger, Andrew P; Wilson, Marenda; Vizeacoumar, Frederick; Datti, Alessandro; Li, Wei; Cooney, Austin J; Barton, Michelle C; Blencowe, Benjamin J; Wrana, Jeffrey L; Dent, Sharon Y R.

Genes Dev ; 29(8): 803-16, 2015 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-25877919

13.

An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14.

Alqawlaq, Samih; Livne-Bar, Izhar; Williams, Declan; D'Ercole, Joseph; Leung, Sara W; Chan, Darren; Tuccitto, Alessandra; Datti, Alessandro; Wrana, Jeffrey L; Corbett, Anita H; Schmitt-Ulms, Gerold; Sivak, Jeremy M.

J Biol Chem ; 296: 100118, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33234594

14.

The hippo pathway: A master regulator of liver metabolism, regeneration, and disease.

Nguyen-Lefebvre, Anh Thu; Selzner, Nazia; Wrana, Jeffrey L; Bhat, Mamatha.

FASEB J ; 35(5): e21570, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33831275

15.

Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods.

Pearson, Joel D; Trcka, Daniel; Lu, Suying; Hyduk, Sharon J; Jen, Mark; Aynaud, Marie-Ming; Hernández, J Javier; Peidis, Philippos; Barrios-Rodiles, Miriam; Chan, Kin; Woodgett, Jim; Mazzulli, Tony; Attisano, Liliana; Pelletier, Laurence; Cybulsky, Myron I; Wrana, Jeffrey L; Bremner, Rod.

Virol J ; 18(1): 99, 2021 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-34001180

16.

Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.

Gregorieff, Alex; Liu, Yu; Inanlou, Mohammad R; Khomchuk, Yuliya; Wrana, Jeffrey L.

Nature ; 526(7575): 715-8, 2015 Oct 29.

Artigo em Inglês | MEDLINE | ID: mdl-26503053

17.

Tissue-specific alternative splicing remodels protein-protein interaction networks.

Ellis, Jonathan D; Barrios-Rodiles, Miriam; Colak, Recep; Irimia, Manuel; Kim, Taehyung; Calarco, John A; Wang, Xinchen; Pan, Qun; O'Hanlon, Dave; Kim, Philip M; Wrana, Jeffrey L; Blencowe, Benjamin J.

Mol Cell ; 46(6): 884-92, 2012 Jun 29.

Artigo em Inglês | MEDLINE | ID: mdl-22749401

18.

MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.

Han, Hong; Irimia, Manuel; Ross, P Joel; Sung, Hoon-Ki; Alipanahi, Babak; David, Laurent; Golipour, Azadeh; Gabut, Mathieu; Michael, Iacovos P; Nachman, Emil N; Wang, Eric; Trcka, Dan; Thompson, Tadeo; O'Hanlon, Dave; Slobodeniuc, Valentina; Barbosa-Morais, Nuno L; Burge, Christopher B; Moffat, Jason; Frey, Brendan J; Nagy, Andras; Ellis, James; Wrana, Jeffrey L; Blencowe, Benjamin J.

Nature ; 498(7453): 241-5, 2013 Jun 13.

Artigo em Inglês | MEDLINE | ID: mdl-23739326

19.

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.

Campbell, Craig I; Samavarchi-Tehrani, Payman; Barrios-Rodiles, Miriam; Datti, Alessandro; Gingras, Anne-Claude; Wrana, Jeffrey L.

J Cell Sci ; 129(18): 3396-411, 2016 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-27521426

20.

SnapShot: The TGFbeta pathway interactome.

Taylor, Ian W; Wrana, Jeffrey L.

Cell ; 133(2): 378.e1, 2008 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-18423207

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